It depends where you are going.
If you are travelling in Europe then the MOT is an issue and needs to be renewed on time.
However, the rest of the world doesn't recognise the MOT, in fact most countries do not even have any inspection requirement.
There is no easy method of taking your vehicle out of Europe for long periods.
However, I can tell you what most people do , which isn't technically legal, but probably the only solution.
Most will SORN the vehicle shortly after it has left the UK.
This puts your DVLA record in an archive state that is easily resurected upon return by getting a new MOT and re taxing it.
The small print says that SORNed vehicles must be in the UK, so you do run a very small risk of being caught contraveining this small infringement. ( small fine at worst )
It's about the only solution but not technically legal
Hope this helps
Neil